Welcome to the Preciseli Podcast: Precision Medicine and Our Co-Founders' Story

Preciseli Podcast

Welcome to the Preciseli Podcast, where we discuss the groundbreaking world of genomics and its revolutionary impact on healthcare. Hosted by Dr. Ilene Klein, Chief Population Health Officer at Preciseli, each episode features conversations with leading experts and innovators. We explore how genetic insights can transform the diagnosis and prevention of diseases like cancer and cardiometabolic disorders, providing listeners with actionable information to navigate their own genetic backgrounds.
Join us to discover how Preciseli is pioneering the future of personalized medicine and learn what drove our founders to start the company.
🔍 What We Talk About:
00:00 Intro to Preciseli Podcast and Host, Dr. Ilene Klein - Nikki Burress
02:22 Dr. Ilene Klein background
03:57 Dr. Ali Torkamani intro
04:40 Ash Misra intro
05:35 Dr. Ali Torkamani background - wants real-world impact from his research
10:14 Ash Misra background - wants to focus on disease prevention and leverage the power of diagnostics
13:34 Preciseli’s Mission to democratize access to precision health diagnostics - Ash Misra
17:03 Polygenic Risk Scores explained - Dr. Ali Torkamani
19:13 Insights from Dr. Torkamani’s work that informs Preciseli’s mission today and in the future - MyGeneRank (do people make better health decisions knowing their genetic risks?) and how we can use genetic information to improve risk stratification (utilizing machine learning to look at combining genetic risk with traditional risk factors to get improved prediction of risk)
22:05 Dr. Torkamani discusses where the field is in terms of accuracy and prediction
24:25 Ash talks about Preciseli’s focus on cancer and why cancer screening based on average risk is not adequate
28:15 Other driving forces driving us towards more personalized health care approaches and the next things on the horizon (explosion of data - genetic data, EHR data, clinical data)
33:13 Ash reiterates the notion of an explosion of genetic data becoming available and combining PRS with monogenic variants, biometric data, and liquid biopsies
36:18 Dr. Torkamani and Ash discuss what makes Preciseli different than other genetic testing companies (Preciseli really supports their members in understanding their risks and their next steps.
42:05 Dr. Torkamani talk about how the change in healthcare will come from the ground up with individuals taking their data to their physicians come up with more personalized health plans
43:37 Ash talks about how Preciseli is looking for partners on the provider side and advocacy side.
🗝️ Key Takeaways:
🔹How genetic information can lead to better health decisions
🔹The importance of personalized risk assessments
🔹Insights from renowned experts in genomics and healthcare
📣 Stay Connected:
🔹Subscribe to our channel for more insights into genetics and personalized medicine
🔹Visit Preciseli.com for more information and updates
🔹Follow us on social media for the latest news and breakthroughs
Instagram: @preciseli.health
X: @preciselihealth
Facebook: @preciseli
🔔 Don't forget to share this video to spread the word on how genetics can revolutionize healthcare!
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information an

Preciseli.com
Dr. Ilene Klein
LinkedIn: @ijkmd
Dr. Ali Torkamani
Twitter: @atorkamani
Ash Misra
LinkedIn: @ashmisra
Nikki Burress
LinkedIn: @nikkivburress
Instagram: @nikkivburress
YouTube: @nikkivburress