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117 From Math to Metagenomics - Titus Brown on Career Journeys and Software Solutions
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A tartalmat a Micro Binfie Podcast and Microbial Bioinformatics biztosítja. Az összes podcast-tartalmat, beleértve az epizódokat, grafikákat és podcast-leírásokat, közvetlenül a Micro Binfie Podcast and Microbial Bioinformatics vagy a podcast platform partnere tölti fel és biztosítja. Ha úgy gondolja, hogy valaki az Ön engedélye nélkül használja fel a szerzői joggal védett művét, kövesse az itt leírt folyamatot https://hu.player.fm/legal.
In this episode of the Micro Binfie Podcast, Andrew Page and Lee Katz interview Titus Brown about his journey from studying math and physics as an undergrad to becoming a bioinformatician focusing on metagenomics and software development. Topics discussed: Titus' background in math, physics, digital evolution research, and developmental biology His transition into bioinformatics to analyze the influx of genomic data in the 1990s Developing early tools for comparative genomics and sequence analysis The philosophy of creating usable software with good documentation Work on transcriptomics, metagenomics, and k-mers at Michigan State Digital normalization and dealing with large sequencing datasets Moving to UC Davis and continuing work on metagenomics and software like khmer and sourmash Thoughts on challenges around data reuse and accessibility in science. Papers: Spacegraphcats - https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02066-4 Sourmash - https://www.biorxiv.org/content/10.1101/2022.01.11.475838v2 IBD exploration - https://dib-lab.github.io/2021-paper-ibd/
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