Building Human-Centered AI Security with Prologis Head of IT Governance & ISO Sue Lapierre

Enterprise AI Defenders

On the 31st episode of Enterprise AI Defenders, hosts Evan Reiser, CEO and co-founder of Abnormal AI, and Mike Britton, CIO at Abnormal AI, sit down with Sue Lapierre, Head of IT Governance & Information Security Officer at Prologis. With 1.3 billion square feet of logistics real estate and $3.2 trillion in goods moving through its facilities, Prologis faces extraordinary stakes. Sue shares how her security team is proactively responding, embedding AI safely across the business while running simulated deepfakes to stress-test resilience. She explains how zero trust begins with human awareness, how internal AI policies ensure transformational security, and why cybersecurity today demands curiosity, not fear.

Quick takes from Sue:

On zero trust being human-first: “We have to also think about zero trust, not only on the technical side, but on the human side.

On internal GPT adoption and focus: “At the very beginning… we locked down all AI except our internal AI Prologis GPT. That helped to focus people into one vector.”​​​​​​​

On simulating deepfake attacks: “We actually hired a third party that created deepfakes and targeted a variety of individuals… we wanted to test if someone fell for it, would they fall all the way… or do we have defenses that would stop it?”

Recent Book Recommendation: Turn the Ship Around by L. David Marquet

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Enterprise AI Defenders is a show where top security executives share how moves to the cloud have created an evolved threat landscape that requires new tools to protect against cybercrime. Find more great lessons from tech leaders and enterprise software experts at https://www.enterprisesoftware.blog/

Enterprise AI Defenders is produced by Josh Meer