Cafe Scientifique: "The Persistence of Memory: How Experience Changes the Brain"

Carnegie Science Center's Podcast

Dr. Alison Barth Associate professor Carnegie Mellon University Department of Biological Science How do our experiences change us? How are memories stored and retrieved? Scientists believe the answers lie in how connections between neurons, called synapses, can be strengthened or weakened over time. The brain contains about 100 billion neurons and 1 quadrillion synapses, so figuring out which ones are changed during learning is the ultimate needle-in-the-haystack problem. Learn how contemporary neuroscientists are tackling this age-old question, using sophisticated, state-of-the-art techniques for neuronal imaging as well as the recording of tiny electrical impulses from task-related neurons. Figuring out what regulates learning promises new methods to boost memory and improve perception or performance. Alison Barth, associate professor in Carnegie Mellon University's Department of Biological Science, will give an introduction to brain plasticity, explaining how molecules become linked to the mind. Dr. Barth studies the organization of and plasticity of neocortical circuits in rodents. Her work centers on how synapses are altered by behavioral experience. She's the recipient of numerous awards, and she holds a patent for the fosGFP transgenic mouse. She is an inventor on multiple applications for other neuroscience-related methods and treatments. Recorded Monday, June 2, 2014, at Carnegie Science Center in Pittsburgh, PA.