The podcast focuses on topics in theoretical/computational neuroscience and is primarily aimed at students and researchers in the field.
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Neuroscience and artificial intelligence work better together. Brain inspired is a celebration and exploration of the ideas driving our progress to understand intelligence. I interview experts about their work at the interface of neuroscience, artificial intelligence, cognitive science, philosophy, psychology, and more: the symbiosis of these overlapping fields, how they inform each other, where they differ, what the past brought us, and what the future brings. Topics include computational n ...
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BI 196 Cristina Savin and Tim Vogels with Gaute Einevoll and Mikkel Lepperød
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1:19:40
Support the show to get full episodes and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists…
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BI 197 Karen Adolph: How Babies Learn to Move and Think
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1:29:31
Support the show to get full episodes and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists…
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On neuro-AI on the boat - part 2 of 2 - with Paul Middlebrooks, Cristina Savin, Tim Vogels, Mikkel Lepperød - #20
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1:21:03
In September Paul Middlebrooks, the producer of the podcast BrainInspired, and I were both on a neuro-AI workshop on a coast liner cruising the Norwegian fjords. We decided to make two joint podcasts with some of the participants where we discuss the role of AI in neuroscience. In this second part we discuss the topic with Cristina Savin and Tim Vo…
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On neuro-AI on the boat - part 1 of 2 - with Paul Middlebrooks, Ken Harris, Andreas Tolias, Mikkel Lepperød - #19
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1:19:26
In September Paul Middlebrooks, the producer of the podcast BrainInspired, and I were both on a neuro-AI workshop on a coast liner cruising the Norwegian fjords. We decided to make two joint podcasts with some of the participants where we discuss the role of AI in neuroscience. In this first part we talk with Mikkel Lepperod, the main organizer abo…
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BI 195 Ken Harris and Andreas Tolias with Gaute Einevoll and Mikkel Lepperød
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1:17:05
Support the show to get full episodes and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists…
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BI 194 Vijay Namboodiri & Ali Mohebi: Dopamine Keeps Getting More Interesting
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1:37:21
Support the show to get full episodes and join the Discord community. https://youtu.be/lbKEOdbeqHo The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written …
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On electric brain signals - solo episode - #18
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1:48:22
Most of what we have learned about the functioning of the living brain has come from extracellular electrical recordings, like the measurement of spikes, LFP, ECoG and EEG signals. And most analysis of these recordings has been statistical, looking for correlations between the recorded signals and what the animal/human is doing or being exposed to.…
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BI 193 Kim Stachenfeld: Enhancing Neuroscience and AI
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1:32:41
Support the show to get full episodes and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists…
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BI 192 Àlex Gómez-Marín: The Edges of Consciousness
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1:30:34
Support the show to get full episodes and join the Discord community. Àlex Gómez-Marín heads The Behavior of Organisms Laboratory at the Institute of Neuroscience in Alicante, Spain. He's one of those theoretical physicist turned neuroscientist, and he has studied a wide range of topics over his career. Most recently, he has become interested in wh…
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On dendritic function - with Yiota Poirazi - #17
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1:27:39
The most prominent visual characteristic of neurons is their dendrites. Even more than 100 years after their first observation by Cajal, their function is not fully understood. Biophysical modeling based on cable theory is a key research tool for exploring putative functions, and today’s guest is one the leading researchers in this field. We talk a…
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BI 191 Damian Kelty-Stephen: Fractal Turbulent Cascading Intelligence
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1:27:51
Support the show to get full episodes and join the Discord community. Damian Kelty-Stephen is an experimental psychologist at State University of New York at New Paltz. Last episode with Luis Favela, we discussed many of the ideas from ecological psychology, and how Louie is trying to reconcile those principles with those of neuroscience. In this e…
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On consciousness - with Christof Koch - #16
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The greatest mystery of all is why a group of atoms, like the ones constituting me, can feel anything. The mind-brain problem has puzzled philosophers for millennia. Thanks to pioneers like Christof Koch, consciousness studies have recently become a legitimate field of scientific inquiry. In this vintage episode, recorded in February 2021, we discu…
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BI 190 Luis Favela: The Ecological Brain
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Support the show to get full episodes and join the Discord community. Luis Favela is an Associate Professor at Indiana University Bloomington. He is part philosopher, part cognitive scientist, part many things, and on this episode we discuss his new book, The Ecological Brain: Unifying the Sciences of Brain, Body, and Environment. In the book, Loui…
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On the simulation tool NEURON - with Michael Hines - #15
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1:26:35
Computational neuroscientists use many software tools, and NEURON has become the leading tool for biophysical modeling of neurons and neural network. Today’s guest has been the leading developer of NEURON since the infancy almost 50 years ago. We talk about how the tool got started and the development up until today’s modern version of the software…
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BI 189 Joshua Vogelstein: Connectomes and Prospective Learning
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1:27:19
Support the show to get full episodes and join the Discord community. Jovo, as you'll learn, is theoretically oriented, and enjoys the formalism of mathematics to approach questions that begin with a sense of wonder. So after I learn more about his overall approach, the first topic we discuss is the world's currently largest map of an entire brain.…
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On the molecular memory code - with Sam Gershman - #14
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1:20:44
The idea that memories are stored in molecules was popular in the middle of the 20th century. However, since the discovery of long-term potentiation (LTP) in the 1970s, the dominant view has been that our memories are stored in synapses, that is, in the connections between neurons. Today, there are signs that the interest in molecular memory is ret…
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On quantum biology - with Johnjoe McFadden - #13
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1:17:20
Is quantum physics important in determining how living systems, including brains, work? Today's guest is a professor of molecular genetics at the University of Surrey in England and explores this question in the book “Life at the edge: The coming of age of quantum biology”. In this “vintage” episode, recorded in late 2019, we talk about how quantum…
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BI 188 Jolande Fooken: Coordinating Action and Perception
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Support the show to get full episodes and join the Discord community. Jolande Fooken is a post-postdoctoral researcher interested in how we move our eyes and move our hands together to accomplish naturalistic tasks. Hand-eye coordination is one of those things that sounds simple and we do it all the time to make meals for our children day in, and d…
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On modeling of signaling pathways inside the neuron - with Avrama Blackwell - #12
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1:31:40
Most computational neuroscientists investigate electric dynamics in neurons or neural networks, but there is also computations going on inside neurons. Here the key dynamical variables are concentrations of numerous different molecules, and the signaling is typically done in cascades of chemical reactions, called signaling pathways. Today’s guest i…
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On synaptic learning rules for spiking neurons - with Friedemann Zenke - #11
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Today’s AI is largely based on supervised learning of neural networks using the backpropagation-of-error synaptic learning rule. This learning rule relies on differentiation of continuous activation functions and is thus not directly applicable to spiking neurons. Today’s guest has developed the algorithm SuperSpike to address the problem. He has a…
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BI 187: COSYNE 2024 Neuro-AI Panel
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Support the show to get full episodes and join the Discord community. Recently I was invited to moderate a panel at the annual Computational and Systems Neuroscience, or COSYNE, conference. This year was the 20th anniversary of COSYNE, and we were in Lisbon Porturgal. The panel goal was to discuss the relationship between neuroscience and AI. The p…
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On large-scale modeling of mouse primary visual cortex - with Anton Arkhipov - #10
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Over the last ten years or so, the MindScope project at the Allen Institute in Seattle has pursued an industrylab-like approach to study the mouse visual cortex in unprecedented detail using electrophysiology, optophysiology, optical imaging and electron microscopy. Together with collaborators at Allen, today’s guest has worked to integrate of thes…
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BI 186 Mazviita Chirimuuta: The Brain Abstracted
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Support the show to get full episodes and join the Discord community. Mazviita Chirimuuta is a philosopher at the University of Edinburgh. Today we discuss topics from her new book, The Brain Abstracted: Simplification in the History and Philosophy of Neuroscience. She largely argues that when we try to understand something complex, like the brain,…
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On origins of computational neuroscience and AI as scientific fields - with Terrence Sejnowski (vintage) - #9
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Today’s guest is a pioneer both in the fields of computational neuroscience and artificial intelligence (AI) and has had a front seat during their development. His many contributions include, for example, the invention of the Boltzmann machine with Ackley and Hinton in the mid 1980s. In this “vintage” episode recorded in late 2019 he describes the …
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BI 185 Eric Yttri: Orchestrating Behavior
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Support the show to get full episodes and join the Discord community. As some of you know, I recently got back into the research world, and in particular I work in Eric Yttris' lab at Carnegie Mellon University. Eric's lab studies the relationship between various kinds of behaviors and the neural activity in a few areas known to be involved in enac…
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On reverse engineering of the roundworm C.elegans - with Konrad Kording - #8
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Today’s guest has argued that the present dominant way of doing systems neuroscience in mammals (large-scale electric or optical recordings of neural activity combined with data analysis) will be inadequate for understanding how their brain works. Instead, he proposes to focus on the simple roundworm C.elegans with only 302 neurons and try to rever…
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BI 184 Peter Stratton: Synthesize Neural Principles
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1:30:47
Support the show to get full episodes and join the Discord community. Peter Stratton is a research scientist at Queensland University of Technology. I was pointed toward Pete by a patreon supporter, who sent me a sort of perspective piece Pete wrote that is the main focus of our conversation, although we also talk about some of his work in particul…
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BI 183 Dan Goodman: Neural Reckoning
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Support the show to get full episodes and join the Discord community. You may know my guest as the co-founder of Neuromatch, the excellent online computational neuroscience academy, or as the creator of the Brian spiking neural network simulator, which is freely available. I know him as a spiking neural network practitioner extraordinaire. Dan Good…
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On topological data analysis and Hopfield-like network models - with Carina Curto - #7
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Over the last decade topological analysis has been established as a new tool for analysis of spiking data. Today’s guest has been a pioneer in adapting this mathematical technique for use in our field and explains concepts and example applications. We also also talk about so-called threshold-linear network model, a generalization of Hopfield networ…
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BI 182: John Krakauer Returns… Again
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience John Krakauer has been on the podcast multiple times (see links below). Today we discuss some topics framed around what he's been working on and thinking about lately. Things like Whether brains actually r…
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On central pattern generators in the spinal cord - with Henrik Lindén - #6
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1:26:33
Not all interesting network activity occurs in cortex. Networks in the spinal cord, the long thin tubular structure extending downwards from the neck, is responsible for setting up rhythmic motor activity needed for moving around. How do these so-called central pattern generators work? Today’s guest has, together with colleagues in Copenhagen, deve…
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BI 181 Max Bennett: A Brief History of Intelligence
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience By day, Max Bennett is an entrepreneur. He has cofounded and CEO'd multiple AI and technology companies. By many other countless hours, he has studied brain related sciences. Those long hours of research h…
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BI 180 Panel Discussion: Long-term Memory Encoding and Connectome Decoding
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Support the show to get full episodes and join the Discord community. Welcome to another special panel discussion episode. I was recently invited to moderate at discussion amongst 6 people at the annual Aspirational Neuroscience meetup. Aspirational Neuroscience is a nonprofit community run by Kenneth Hayworth. Ken has been on the podcast before on…
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On how vision works - with Li Zhaoping - #5
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We know a lot about of how neurons in the primary visual cortex (V1) of mammals respond to visual stimuli. But how does the vast information contained in the spiking of millions of neurons in V1 give rise to our visual percepts? The guest’s theory is that V1 acts as a “saliency detector” directing the gaze to the most important object in the visual…
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BI 179 Laura Gradowski: Include the Fringe with Pluralism
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience Laura Gradowski is a philosopher of science at the University of Pittsburgh. Pluralism is roughly the idea that there is no unified account of any scientific field, that we should be tolerant of and welcom…
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On multi-area cortex models - with Sacha van Albada - #4
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A key goal of computational neuroscience is to build mathematical models linking single-neuron activity to systems-level activity. The guest has taken some bold steps in this direction by developing and exploring a multi-area model for the macaque visual cortex, and later also a model for the human cortex, using millions of simplified spiking neuro…
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BI 178 Eric Shea-Brown: Neural Dynamics and Dimensions
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience Eric Shea-Brown is a theoretical neuroscientist and principle investigator of the working group on neural dynamics at the University of Washington. In this episode, we talk a lot about dynamics and dimensi…
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On the neural code - with Arvind Kumar - #3
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It is widely thought that spikes (action potentials) are the main carrier of information in the brain. But what is the neural code, that is, what aspects of the spike trains carry the information? The detailed temporal structure or maybe only the average firing rate? And is there information in the correlation between spike trains in populations of…
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BI 177 Special: Bernstein Workshop Panel
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Support the show to get full episodes and join the Discord community. I was recently invited to moderate a panel at the Annual Bernstein conference - this one was in Berlin Germany. The panel I moderated was at a satellite workshop at the conference called How can machine learning be used to generate insights and theories in neuroscience? Below are…
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On biophysics of computation – with Christof Koch - #2
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Starting from the pioneering work of Hodgkin, Huxley and Rall in the 1950s and 60s, we have a well-founded biophysics-based mathematical understanding of how neurons integrate signals from other neurons and generate action potentials. Today’s guest wrote the classic book “Biophysics of Computation” on the subject in 1998. We discuss its contents, w…
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BI 176 David Poeppel Returns
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Support the show to get full episodes and join the Discord community. David runs his lab at NYU, where they stud`y auditory cognition, speech perception, language, and music. On the heels of the episode with David Glanzman, we discuss the ongoing mystery regarding how memory works, how to study and think about brains and minds, and the reemergence …
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On models of the mind - with Grace Lindsay - #1
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The book “Models of the Mind” published in 2021 gives an excellent popular account of the history and questions of interest in theoretical neuroscience. I could think of no other person more suitable to invite for the inaugural episode of the podcast than its author Grace Lindsay. In the podcast we discuss highlights from the book as well as recent…
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BI 175 Kevin Mitchell: Free Agents
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience Kevin Mitchell is professor of genetics at Trinity College Dublin. He's been on the podcast before, and we talked a little about his previous book, Innate – How the Wiring of Our Brains Shapes Who We Are. …
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BI 174 Alicia Juarrero: Context Changes Everything
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Check out my free video series about what's missing in AI and Neuroscience Support the show to get full episodes and join the Discord community. Alicia Juarrero is a philosopher and has been interested in complexity since before it was cool. In this episode, we discuss many of the topics and ideas in her new book, Context Changes Everything: How Co…
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BI 173 Justin Wood: Origins of Visual Intelligence
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Support the show to get full episodes and join the Discord community. In the intro, I mention the Bernstein conference workshop I'll participate in, called How can machine learning be used to generate insights and theories in neuroscience?. Follow that link to learn more, and register for the conference here. Hope to see you there in late September…
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BI 172 David Glanzman: Memory All The Way Down
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Support the show to get full episodes and join the Discord community. David runs his lab at UCLA where he's also a distinguished professor. David used to believe what is currently the mainstream view, that our memories are stored in our synapses, those connections between our neurons. So as we learn, the synaptic connections strengthen and weaken u…
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BI 171 Mike Frank: Early Language and Cognition
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience My guest is Michael C. Frank, better known as Mike Frank, who runs the Language and Cognition lab at Stanford. Mike's main interests center on how children learn language - in particular he focuses a lot o…
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BI 170 Ali Mohebi: Starting a Research Lab
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience In this episode I have a casual chat with Ali Mohebi about his new faculty position and his plans for the future. Ali's website. Twitter: @mohebialPaul Middlebrooks által
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BI 169 Andrea Martin: Neural Dynamics and Language
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Support the show to get full episodes and join the Discord community. Check out my free video series about what's missing in AI and Neuroscience My guest today is Andrea Martin, who is the Research Group Leader in the department of Language and Computation in Neural Systems at the Max Plank Institute and the Donders Institute. Andrea is deeply inte…
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BI 168 Frauke Sandig and Eric Black w Alex Gomez-Marin: AWARE: Glimpses of Consciousness
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Check out my free video series about what's missing in AI and Neuroscience Support the show to get full episodes and join the Discord community. This is one in a periodic series of episodes with Alex Gomez-Marin, exploring how the arts and humanities can impact (neuro)science. Artistic creations, like cinema, have the ability to momentarily lower o…
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