Could Worms REALLY Be the Key to Curing Autoimmune Diseases?

Life Sciences 360

In this episode, we dive deep into a fascinating topic worm-derived therapeutics with our special guest Andrea, the founder and CEO of Holoclara. Did you know that autoimmune and allergic diseases were rare before the 1900s? What changed? Andrea shares groundbreaking insights into how worms, which have lived inside humans for millions of years, secrete molecules that could balance our immune system and help us tackle these diseases.
From her early research days at Caltech to founding Holoclara, Andrea walks us through her journey, including:
Chapters:
00:00 - The History of Autoimmune Diseases
01:24 - Why Watch This Video?
02:36 - Andrea’s Research Background
05:49 - The Turning Point: Entrepreneurship and Therapeutics
09:02 - Worms and Human Health: The Therapeutic Connection
11:32 - Worm Communication and Therapeutics
15:24 - The Industrial Revolution and Autoimmune Diseases
19:33 - How Worm-Derived Therapeutics Work
21:33 - Overcoming Challenges in Biotech
24:21 - The Future of Worm-Derived Therapeutics
25:48 - Studying Different Worm Species
26:57 - Life Outside Research
29:29 - Final Takeaway: Embracing Feedback and Opportunity
Andrea also discusses the personal and scientific breakthroughs that led her to create Holoclara, a company dedicated to harnessing worm-derived molecules for modern medical solutions. Learn how roundworms evolved to produce tools that harmonize our immune system, and how these ancient organisms may hold the key to treating modern diseases.
If you're intrigued by this incredible scientific journey and its implications for health, don't miss this episode!
🔗 Learn more about Holoclara: https://www.holoclara.com/
Linkedin: Andrea Choe, Co-Founder and CEO Holoclara
https://www.linkedin.com/in/andreachoe/
Company page: https://www.linkedin.com/company/holoclara-inc/
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💬 Let us know in the comments: Did you know worms could be this powerful?
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