Razib Khan's Unsupervised Learning podcast

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A tartalmat a Razib Khan biztosítja. Az összes podcast-tartalmat, beleértve az epizódokat, grafikákat és podcast-leírásokat, közvetlenül a Razib Khan vagy a podcast platform partnere tölti fel és biztosítja. Ha úgy gondolja, hogy valaki az Ön engedélye nélkül használja fel a szerzői joggal védett művét, kövesse az itt leírt folyamatot https://hu.player.fm/legal.

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The Final Flight of Captain Forrester

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5 napja5d ago

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A woman’s search for her father—a pilot who disappeared during a mission in Vietnam—collides with the fight over what we owe those who never returned from war. From the producers of "America's Girls," and hosted by Texas Monthly writer Josh Alvarez, the show debuts April 2025. Texas Monthly Audio subscribers get early access to the show, plus bonus episodes and more subscriber-only audio. Visit texasmonthly.com/audio to learn more.

Razib Khan's Unsupervised Learning

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Razib Khan engages a diverse array of thinkers on all topics under the sun. Genetics, history, and politics. See: http://razib.substack.com/

250 epizódok

#Biology #Social Sciences #Culture #Politics #Genetics #Science #Natural Sciences #History #Society #Razib Khans

Razib Khan's Unsupervised Learning

329 subscribers

updated körülbelül 6 órája

Megosztás

Sorozat kép•Feed

Razib Khan engages a diverse array of thinkers on all topics under the sun. Genetics, history, and politics. See: http://razib.substack.com/

250 epizódok

#Biology #Social Sciences #Culture #Politics #Genetics #Science #Natural Sciences #History #Society #Razib Khans

Minden epizód

Razib Khan's Unsupervised Learning

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Bonus monologue: man the hybrid monster 19:35

6 hours19:35

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Listák

Tetszik

Kedvelt

19:35

Today, Razib talks about a new paper, A structured coalescent model reveals deep ancestral structure shared by all modern humans : Understanding the history of admixture events and population size changes leading to modern humans is central to human evolutionary genetics. Here we introduce a coalescence-based hidden Markov model, cobraa, that explicitly represents an ancestral population split and rejoin, and demonstrate its application on simulated and real data across multiple species. Using cobraa, we present evidence for an extended period of structure in the history of all modern humans, in which two ancestral populations that diverged ~1.5 million years ago came together in an admixture event ~300 thousand years ago, in a ratio of ~80:20%. Immediately after their divergence, we detect a strong bottleneck in the major ancestral population. We inferred regions of the present-day genome derived from each ancestral population, finding that material from the minority correlates strongly with distance to coding sequence, suggesting it was deleterious against the majority background. Moreover, we found a strong correlation between regions of majority ancestry and human–Neanderthal or human–Denisovan divergence, suggesting the majority population was also ancestral to those archaic humans.…

Razib Khan's Unsupervised Learning

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John Sailer: a time of troubles in higher education 1:22:25

1 day1:22:25

1:22:25

On this episode of the podcast Razib talks to John Sailer. Sailer is currently the director of higher education policy and a senior fellow at the Manhattan Institute. He covers issues of academic freedom, free speech, and ideological capture in higher education. Sailer has written for the Wall Street Journal, the Free Press and Tablet Magazine. Sailer holds a master’s degree in philosophy and education from Columbia University, and a bachelor’s degree in politics, philosophy, and economics from The King’s College. Prior to joining the Manhattan Institute, he was a senior fellow at the National Association of Scholars. Following on last week’s podcast with Jacob Shell , Razib continues to discuss the rise and fall of woke politics in academia, and the current backlash exploding out of the Trump administration. Sailer discusses his previous work back to 2020 showing how blatant universities became in their discriminatory policies against white males in particular, and how easy it was to demonstrate this dynamic with even the most minimal level of due diligence like freedom of information requests. They also discuss the reality that universities are attempting to adjust to a new landscape with the administration pressuring them to revoke DEI policies, while many faculty are urging that they instead dig in their heels. Higher education is adapting, but Sailer argues that since fundamental values have not changed, some evasion is to be expected.…

Razib Khan's Unsupervised Learning

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Jacob Shell: academia must diversify or die 1:43:54

9 napja1:43:54

1:43:54

On this episode of Unsupervised Learning Razib talks to Jacob Shell . Shell is a professor of geography at Temple University and author of Transportation and Revolt: Pigeons, Mules, Canals , and the Giants of the Monsoon Forest: Living and Working with Elephants . Educated at Columbia and Syracuse universities, Shell is active on social media, where he comments extensively on the politicization of the academy. The conversation begins with Shell’s piece in Compact Magazine , To Save Academia, Hire Conservatives . The more than 3,000-word essay argues that academia must diversify ideologically to save itself, but also engage in a wider range of scholarship. Shell points out that US academia has become an ideological monoculture, with an overwhelming dominance of left-leaning faculty, especially at elite institutions. This imbalance, driven by extreme partisan ratios in fields like anthropology, leaves universities politically vulnerable and out of step with the broader public. He challenges the common view that this trend is due to self-selection, or the “pipeline problem,” suggesting instead that informal screening mechanisms discourage or exclude conservative scholars. Shell also argues that the grant system encourages conformity and limits academic freedom. More audaciously, he argues that some academics should be singled out by their peers, whether through their institution or professional organizations,t when they engage in politically motivated misrepresentation of their scholarship. Ultimately, Shell insists that academia’s unique role in public life is to observe and understand the world, not to risk co-option as an arm of any political movement.…

Razib Khan's Unsupervised Learning

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Matt Welch: from blog pioneer to podcasting mainstay 1:28:10

11 napja1:28:10

1:28:10

On this episode of Unsupervised Learning Razib talks to Matt Welch . He co-founded the Prague-based newspaper Prognosis in the early 1990’s and later worked as an opinion section editor for the Los Angeles Times. From 2008-2016, Welch served as editor-in-chief of Reason magazine, where he currently holds the position of editor-at-large. He co-authored The Declaration of Independents: How Libertarian Politics Can Fix What's Wrong with America and wrote McCain: The Myth of a Maverick . Today, Welch co-hosts The Fifth Column podcast with Kmele Foster and Michael Moynihan. Razib and Welch first go back to his days in Eastern Europe, and how they shaped his views on foreign policy, making him somewhat heterodox for someone whose primary political inclinations favor libertarianism. Welch discusses how wild, hopeful and chaotic the 1990’s were in the former Eastern Bloc after the fall of the Iron Curtain and the end of Communism. He also argues that these nations had strong historic and contemporary geopolitical reasons to fear the former Soviet Union, and so pushed for the eastward expansion of NATO. Razib makes the Russian case that its turn away from the West in the 2000’s was in response to America’s strategy of encirclement, but Welch dismisses this as Russian revisionism. He believes that at the end of the day Soviet-era elites retained an imperial attitude toward Eastern and Central Europe rooted in a centuries-long assumption of Russian hegemonic status in the region. Next, retreating from abstruse foreign policy, Razib and Welch discuss the early days of the blogosphere, in 2001/2002. Then, Welch coined the term “warblogger,” and envisaged a scenario where post-partisan citizen-journalists would play an essential role in the information ecosystem of the 21st century. He discusses his disappointment with the reemergence of partisanship within the blogosphere, as well as the disappointments of post-9/11 interventionism. Welch also talks about the Tea Party, and its connection, and ultimate disconnect, from libertarianism. They also discuss how the Tea Party energy was eventually transferred to the ideologically heterodox and often anti-libertarian Trump movement. Finally, Welch talks about his latest primary venture, the successful The Fifth Column podcast. Razib asks if the current age of podcasting is analogous to the early blogosphere. Welch talks about how organically and gradually The Fifth Column came into being, and the growing pains with greater professionalization. He also addresses their future on The Fifth Column, with a new shift toward video, while continuing the informal and candid nature of the discussions.…

Razib Khan's Unsupervised Learning

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Bonus monologue: ancient North Africans and the Green Sahara 18:12

11 napja18:12

18:12

On this episode of Unsupervised Learning Razib comments on a new paper in Nature , Ancient DNA from the Green Sahara reveals ancestral North African lineage . Here is the abstract: Although it is one of the most arid regions today, the Sahara Desert was a green savannah during the African Humid Period (AHP) between 14,500 and 5,000 years before present, with water bodies promoting human occupation and the spread of pastoralism in the middle Holocene epoch1. DNA rarely preserves well in this region, limiting knowledge of the Sahara’s genetic history and demographic past. Here we report ancient genomic data from the Central Sahara, obtained from two approximately 7,000-year-old Pastoral Neolithic female individuals buried in the Takarkori rock shelter in southwestern Libya. The majority of Takarkori individuals’ ancestry stems from a previously unknown North African genetic lineage that diverged from sub-Saharan African lineages around the same time as present-day humans outside Africa and remained isolated throughout most of its existence. Both Takarkori individuals are closely related to ancestry first documented in 15,000-year-old foragers from Taforalt Cave, Morocco2, associated with the Iberomaurusian lithic industry and predating the AHP. Takarkori and Iberomaurusian-associated individuals are equally distantly related to sub-Saharan lineages, suggesting limited gene flow from sub-Saharan to Northern Africa during the AHP. In contrast to Taforalt individuals, who have half the Neanderthal admixture of non-Africans, Takarkori shows ten times less Neanderthal ancestry than Levantine farmers, yet significantly more than contemporary sub-Saharan genomes. Our findings suggest that pastoralism spread through cultural diffusion into a deeply divergent, isolated North African lineage that had probably been widespread in Northern Africa during the late Pleistocene epoch.…

Razib Khan's Unsupervised Learning

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Andrew Song: cooling the planet with technology 55:04

18 napja55:04

55:04

On this episode of Unsupervised Learning , Razib talks to Andrew Song , co-founder of Make Sunsets . An NYU graduate with a degree in economics, Song was a member of the Y Combinator class of winter 2016. Before becoming a founder, Song worked at firms involved in data analytics and artificial intelligence. A repeat attendee at the Founders Fund “Hereticon” conference, Song’s company has been profiled IEEE Spectrum , The New York Times and NPR . Razib and Song first talk about the current state of climate, or more precisely, climate change and anthropogenic global warming. Song argues that the emission-reduction strategy has fundamentally failed, and global warming is inevitable absent a drastic strategy shift. Enter geoengineering, the deliberate large-scale manipulation of an environmental process that affects the earth. In the context of global warming Song proposes that humans engage in proactive efforts to cool the world. His company, along with a similar Israeli startup, proposes to introduce particulate matter into the stratosphere to reflect back some of the sun’s radiation. Razib asks Song what the reaction has been, given that the atmosphere is a public resource, and how he proposes to eventually make it a revenue-generating business through government contracts. More generally, Razib and Song talk about other geoengineering projects, including Augustus Doricko’s dream of increasing precipitation through his Rainmaker firm.…

Razib Khan's Unsupervised Learning

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Zineb Riboua: realism in foreign policy in 2025 1:07:28

24 napja1:07:28

1:07:28

Today on Unsupervised Learning Razib talks to Zineb Riboua , a research fellow and program manager of Hudson Institute’s Center for Peace and Security in the Middle East. She specializes in Chinese and Russian involvement in the Middle East, the Sahel, and North Africa, great power competition in the region, and Israeli-Arab relations. Riboua’s pieces and commentary have appeared in the Wall Street Journal, Foreign Policy , the National Interest , the Jerusalem Post and Tablet among other outlets. She holds a master’s of public policy from the McCourt School of Public Policy at Georgetown University. She did her undergraduate studies in France, where she attended French preparatory classes and HEC Paris’ Grande Ecole program. Her Substack is Beyond the Ideological . Razib and Riboua discuss the Trump administration’s theory of tariffs as a tool of foreign policy and his attitudes toward multilateral diplomacy. They explore whether any principle beyond power and dominance underlies the current administration’s approach, and consider the role of principles and values in foreign policy. Riboua elaborates a realist perspective in line with the thinking of Henry Kissinger. States have interests and abilities to execute on those interests; idealism is secondary. Riboua also discusses the fact that Trump seems attuned to how foreign politicians relate to the American domestic scene. He seems willing to punish those abroad whom he perceives to be favorable to his political enemies and reward those who are personally favorable toward him. Razib then asks Riboua about the geopolitics of her native Morocco, a relatively stable monarchy on northwest Africa’s edge that has promoted moderate Islam, a good relationship with Europe and maintained a stable democracy.…

Razib Khan's Unsupervised Learning

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Mark Lutter: charter cities and the urban future 1:03:03

5 weeks1:03:03

1:03:03

On this episode of Unsupervised Learning Razib talks to Mark Lutter. Lutter is an urban development expert known for his work on charter cities—new urban areas aimed at fostering economic growth and progress. He is the Founder and Executive Chairman of the Charter Cities Institute, a nonprofit dedicated to building the ecosystem for charter cities, as well as the CEO of Braavos Cities, a charter city development company. He holds a PhD in economics from George Mason University, and a BS in mathematics from the University of Maryland, College Park. His interests span progress studies, governance, social dynamics and institution-building, with a belief that creating new cities can spark cultural and economic advancements similar to historical periods like the Renaissance or the Dutch Golden Age. He has been published or quoted in outlets like the Financial Times , The New Yorker , and The Chicago Tribune . Lutter and Razib discuss diverse topics, from the difficulties of the Prospera project in Honduras, to the possibility of developing San Francisco’s Presidio into an Asian-style super-city. They explore the various pitfalls and possibilities faced when attempting to create new jurisdictions in developing nations in the Caribbean and Latin America, along with the major obstacles to urban innovation in the USA. Lutter outlines the economic case for charter cities, along with the normative values that undergird their creation as bastions of liberty and laboratories of cultural experimentation. Finally, they discuss the Trump administration’s openness to the idea of the “Freedom City” in the Presidio, along with local opposition to the project.…

Razib Khan's Unsupervised Learning

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Graeme Wood: Germany's turn to the right 1:05:30

6 weeks1:05:30

1:05:30

On this episode of Unsupervised Learning, Razib talks to Graeme Wood. Wood is a staff writer at The Atlantic , where he usually covers geopolitics and international affairs. His work ranges from a profile of Richard Spencer , the American white nationalist public figure with whom he went to high school with, to the Islamic State . He is the author of The Way of the Strangers: Encounters with the Islamic State . Wood grew up in Dallas, Texas, and graduated from Harvard College. He also studied at the American University in Cairo, Indiana University and Deep Springs College. Today Razib talks to Wood about his piece in The Atlantic, Germany’s Anti-Extremist Firewall Is Collapsing . Wood addresses the economic malaise of contemporary Germany, in particular, the former East Germany, and how that is impacting the national cultural climate. More concretely, they consider why the right-wing Alternative For Deutschland (AFD) party is so popular, and its transformation from an anti-EU party to an anti-migrant party. Wood emphasizes that Germany has become a highly polarized society when it comes to ethnicities, with very cosmopolitan cities, but small towns in rural eastern provinces where he recalls feeling like possibly the only non-white face at the local beer hall (his father is a white American while his mother is ethnically Chinese). Razib muses whether German multiculturalism as an ideology has allowed for more, not less racism, while Wood reflects on his multi-decade experience visiting the nation as an outsider.…

Razib Khan's Unsupervised Learning

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Leighton Woodhouse: against the rise of the anti-woke cancel culture and MAGA cultural hegemony 1:27:09

7 weeks1:27:09

1:27:09

On this episode of Unsupervised Learning Razib welcomes Leighton Akira Woodhouse back to the podcast for his third visit . Woodhouse is a journalist and documentarian based in Oakland, California. He grew up in Berkeley, and was a doctoral student in Sociology at UC Berkeley. After leaving academia he contributed to outlets like The Intercept, UnHerd and The Nation, before starting his own Substack, Social Studies . He hosts Le Pod with Lee Fang . Woodhouse was a major left-wing critic of the excesses of woke culture, and now he has turned his skeptical eye upon the regnant MAGA cultural political complex. In posts like MAGA Globalism and Neoliberalism is Back! Woodhouse observes how the Trump administration seems to have turned its back on the “working-class politics” espoused by J. D. Vance in favor of the sort of free-market libertarianism preferred by tech oligarchs like Elon Musk. Razib outlines the divisions in the Trump administration between Steve Bannon and the tech-globalists around Musk, and how these divisions explain online discord. Woodhouse though argues that Trump has clearly sided with Musk, allowing the government to be captured by monied interests that will profit from the military-industrial complex. He also argues that MAGA in power shows the same tendency of the woke movement in terms of clamping down on free speech now that the Right is ascendant. Woodhouse argues that the Right is now using the same tools of cultural hegemony that the woke Left used before 2024. He argues that institutional politicization today is very similar to the dynamic he saw before 2024 on the part of the woke Left.…

Razib Khan's Unsupervised Learning

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Kevin Klatt: Nutrition, health, MAHA and GLP-1 1:20:04

8 weeks1:20:04

1:20:04

On this episode of Unsupervised Learning Razib talks to Kevin Klatt , a metabolism researcher , dietitian and science communicator . Klatt holds a BA in biological anthropology from Temple University and a PhD in Molecular Nutrition from Cornell University. Before a current appointment as a research scientist at UC Berkeley, he was a postdoctoral fellow at Baylor College of Medicine. Klatt’s primary platform to communicate about nutrition, health and molecular biology is his Substack . He is also an associate editor at the American Journal of Clinical Nutrition . Recently Klatt has been writing about the “MAHA” pivot, “Make America Healthy Again,” driven by RFK Jr.’s appointment as head of Health and Human Sciences. Razib and Klatt talk about new directions driven by RFK Jr.'s focus on preventative health and skepticism of pharmaceuticals. Klatt points out that the past two decades have seen a massive shift away from funding nutritional studies, in contrast to the massive budgets of big pharma. He argues that we now really find ourselves without enough information to outline a public health policy given the underfunding of nutritional cohort studies. If MAHA is going to be a serious movement, it needs to drive a reallocation of funds. Razib and Klatt also touch on the cultural shift over the last decade on the Right, where something like “raw milk” switched from being coded as left-wing to being squarely right-wing. They also consider mounting skepticism of mainstream medicine, including vaccination, that seems to be associated with MAHA and in particular RFK Jr. Klatt also addresses the role that GLP-1 drugs are having in driving down obesity rates in the USA, and how pervasive their use might be in the near future.…

Razib Khan's Unsupervised Learning

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Charles Murray: 50 years on the public scene 59:57

9 weeks59:57

59:57

On this episode of Unsupervised Learning , friend of the podcast, Charles Murray returns to chat with Razib again. Murray has been a public intellectual and scholar since the 1970’s. He is the author of Losing Ground , The Bell Curve , Human Accomplishment , Real Education , Coming Apart and What it means to be a libertarian and Human Diversity , among others. Born in 1943 in Newton, Iowa, Murray has a BA from Harvard, an MA and PhD from MIT, and did a 1960’s stint in the Peace Corps in Thailand. He has held positions at the American Institutions for Research, the Manhattan Institute and the American Enterprise Institute. More than four years after their last conversation , and seven years after his official retirement, Murray reflects with Razib on where he sees America going in the next decade, and what has surprised him about the last 25 years. Razib asks what it is like to be a long-standing “Never Trump conservative” and a libertarian in Trump’s populist America. They also discuss the end of the “awokening” that began in the mid-2010s, and whether Murray’s long exile from notice and acknowledgement from mainstream opinion-leaders and tastemakers is at an end. Murray also addresses the ideological fractures he sees on the right, and how America will deal with the last generation of mass immigration that has altered the US’ demographic balance. They also discuss how taboo it still is to talk about group differences in cognitive performance, and whether America will be able to face the reality of demographics and the social consequences thereof in the 21st century.…

Razib Khan's Unsupervised Learning

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Titus Techera: Post-Modern Conservative in a post-national Europe 1:26:24

10 weeks1:26:24

1:26:24

On this episode of Unsupervised Learning , Razib talks to Titus Techera , a Romanian living in Budapest, but commenting extensively on American and European culture. He is the Executive Director of the American Cinema Foundation, International Coordinator of the National Conservatism Conference and is a primary contributor to the Substack PostModernConservative . Techera also hosts a podcast for the American Cinema Foundation. Razib first talks to Techera about the 2024 Romanian presidential election that was overturned by the courts over accusations of Russian interference. Techera explains the social and cultural context of the candidate initially declared victorious against a backdrop of Romanian society’s typical stock characters. Techera also discusses the tension between having a nation-state with a distinctive character and becoming part of the broader EU project that is attempting to forge unity across 27 countries. He then addresses what a “Postmodern Conservative” is in the context of the arts. Perhaps most importantly, PostModern Conservatives take the 20th century and the modernist period seriously; they are not simply reactionaries who want to return to the 19th century. Conservatives who value the arts and culture cannot simply roll the tape back; they have to engage with what has come before. Razib and Techera also consider how inferences from the sciences, like the rejection of the “blank slate,” might influence the arts. They also discuss their disagreements about the latest Dune films, Techera prefers David Lynch’s attempt to adapt the book in 1984 to Denis Villeneuve’s 2021 version.…

Razib Khan's Unsupervised Learning

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Nathan Lents: Sex, truths and gender wars 2:09:01

10 weeks2:09:01

2:09:01

On this episode of Unsupervised Learning Razib talks to Nathan Lents about his new book, The Sexual Evolution: A Provocative Look at Sexual Behavior Through the Lens of Evolution . A professor at John Jay College in New York City, Lents earned a Ph.D. in Pharmacological and Physiological Sciences in 2004 at Saint Louis University School of Medicine, and did his postdoctoral fellowship in cancer genomics at NYU Medical Center. Lents’ research ranges from the evolution of molecular mechanisms to behavioral ecology. He is also the author of Not So Different: Finding Human Nature in Animals and Human Errors: A Panorama of Our Glitches, from Pointless Bones to Broken Genes . Lents reached out to Razib after hearing his podcast with Conn Carroll , about his book Sex and the Citizen: How the Assault on Marriage Is Destroying Democracy . Lents felt that Carroll overemphasized the role of monogamy during humanity’s long forager phase, and more precisely, failed to distinguish social monogamy and genetic monogamy. As noted in The Sexual Evolution , many socially monogamous species, like most birds, engage in enough extra-pair copulation so that genetic fidelity is considerably lower than 100%. Razib and Lents then go back to first principles, talking about the origins of sex, and its persistence in the face of the two-fold cost of reproduction in dimorphous organisms. They discuss why specialized males and females exist in complex organisms as distinct as flowering plants and humans. Lents also discusses the reviews empirical literature on homosexual behavior, variation in sex differences across many classes of organisms and the application of evolutionary thinking to our understanding of the human past. Then they discuss the relevance of evolutionary biology for understanding the human present, and our current debates about marriage, sex and gender. Finally, they consider the differences between sex and gender, and the idea that both can be conceptualized in a nonbinary fashion.…

Razib Khan's Unsupervised Learning

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Antonio Regalado: CRISPR babies 6 years later 1:16:44

10 weeks1:16:44

1:16:44

Today Razib talks to Antonio Regalado , reporter at MIT Technology Review . Regalado covers how technology is changing medicine and biomedical research. Before joining MIT Technology Review in 2011, he lived in São Paulo, Brazil, where he wrote about science, technology, and politics in Latin America for Science and other publications. From 2000 to 2009, he was a science reporter and foreign correspondent at the Wall Street Journal . Among the many stories Regalado has broken was the prenatal sequencing of Razib’s son in 2014, but on this episode they talk about another scoop: his 2018 reporting on the “CRISPR babies” (listen to a podcast on the topic with Regalado on The Insight ). Starting in 2024, the scientist who led the 2018 gene-editing of two babies in China, He Jiankui, seemed to embrace a new role as self-appointed social media evangelist and oracle, mostly about his own future. Regalado talks about what he thinks the Chinese scientist is up to, where the field of CRISPR-gene editing is at present and where it is going. Razib and Regalado also discuss the rise and fall, and future prospects, of CRISPR biotech startups attempting to develop therapies that deploy gene-editing. Regalado also muses on the emergence of companies that provide genomic technologies and services like embryo screening in the “gray market” away from public view.…

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