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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance ...
 
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IN THIS EPISODE OF THE HUMAN UPGRADE™…you’re going to learn how to work with your own biology, adapt to adversity, and get resilient AF. Doctor, educator and entrepreneur Dr. Molly Maloof joins the show in person in Austin, Texas, to talk about her debut book, “The Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Be…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… board-certified OB/GYN and “menopause warrior” Mary Claire Haver, M.D., joins the show to give women a toolkit to manage what comes before, during and after menopause. She explains the science of women’s hormones, physiology and brain during the menopausal transition. She breaks down the studies, risks, and ag…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™…Susanna Soeberg, Ph.D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism. When it comes to biohacking, a few things rise …
 
Leela Quantum Tech sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up. Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode #809 and its benefits on body function, cellular voltage and c…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™…Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research. Dr. Palmer integrated existing theories and research into one unifying theory—the brain energy theory of mental illness that’s roo…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll meet Gloria Mark, Ph.D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking. As a Chancellor’s…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive. Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their familie…
 
Neurohacker Collective sponsored this episode. IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics. When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and Dr. Andrew Weil recorded live at True Food Kitchen in Phoenix, Arizona. Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwi…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn: what “real” love means (hint: it’s not found or earned) and how to recognize it in your life. how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love …
 
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Ari Whitten, Ph.D. (Cand.), CES, PES, explains how to double your energy through improved resilience, cell defense, nutrition and supplementation. In his newest book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” Ari explains that 5.4 million adult…
 
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Steven Gundry, M.D., explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens. He de…
 
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… natural vision expert Claudia Muehlenweg explains how you can take better care of your eyes and improve your vision. Her work is based in the Bates Method. She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually ca…
 
In this Episode of The Human Upgrade™… Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also …
 
Viome sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more density in your gut microbiome, but there’s more diversity in your oral micro…
 
Pendulum sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system,…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone, not only famili…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips. Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology …
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100? Dan, an explorer, National …
 
(ZBiotics sponsored this episode.) IN THIS EPISODE OF THE HUMAN UPGRADE™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations. Zack Abbott, CEO & co-founder of ZBiotics, joins this 1,00…
 
In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Sperm that swim together increase their chances of fertilization Late-night eating is worse than you thought Metabolic markers can be measured th…
 
Timeline Nutrition sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria. “It takes all the ce…
 
IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn: how your microbiome continually evolves and why that matters to the state of your gut and body functions. how to strengthen the antiviral…
 
Eight Sleep sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was …
 
BiOptimizers sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks…
 
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