The Duke Clinical Research Institute is drawing on gold-standard research and real-world evidence to bring you Beyond the Endpoint, a podcast that is demystifying clinical research and healthcare through conversations with renowned clinicians and scientists.
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It's Not Just the Scale: Supporting Sustainable Change in Obesity Treatment
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32:14In the first of a three-part series on obesity and GLP-1 medications, our guest Jennifer Norris shares the evolving landscape of obesity treatment. The conversation addresses common misconceptions and examines how GLP-1 medications, such as Ozempic, have transformed care alongside surgery and lifestyle interventions.…
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Beyond the Headlines: Funding Research, Vaccines, Sleep Health, and AI in Healthcare
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26:43The "Beyond the Headlines" series returns with summer healthcare and research news. Hosts Manesh Patel and Emily O'Brien discuss misconceptions about research funding, a Danish study on vaccine safety, the potential impacts of poor sleep, and how AI tools are transforming medical practice and training. Tags: #medicalnews #healthnews #research #clin…
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Understanding Autism: Insights from Research and Practice
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26:02Ushering in the second season of Beyond the Endpoint, Lauren Franz, MBChB, MPH, interim director of the Duke Center for Autism and Brain Development, joins Manesh Patel and Emily O'Brien for an in-depth conversation about autism research, care, and community. Franz explains what autism is as a neurodevelopmental spectrum condition and how our under…
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Playing to Advance Care: A Championship Mindset in Clinical Research
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34:35What do championship sports teams and successful research institutions have in common? In the season finale of Beyond the Endpoint, Dr. Adrian Hernandez joins hosts Manesh Patel and Emily O’Brien to break down what clinical research institutions can learn from their counterparts on the court. From basketball dynasties to resilient mindsets, Dr. Her…
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Beyond the Headlines: Protein myths. Anti-aging hype. Autism research. A new diabetes drug?
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24:53In this new episode of the Beyond the Endpoint series, “Beyond the Headlines,” hosts Emily O’Brien and Manesh Patel break down what’s you should know about these trending medical topics. From hype to headlines—get clinical insight that goes deeper. Access resources related to this episode https://dcri.org/blog/ep-9-beyond-headlines187880…
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Stepping Up: From Curiosity to Confidence — What to Know Before You Join a Trial
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24:41Why do people volunteer for clinical trials — and what should they know before doing so? In this episode of Beyond The Endpoint, we explore common questions, reasons, and myths about clinical trial participation. Hosts Manesh Patel and Emily O’Brien talk with guest Krista Camuglia, a Research Practice Manager with the Duke Heart Center Clinical Res…
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Stepping Up: Why Participate in Clinical Research?
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32:13In this episode, cancer survivor Katie Ortman-Doble opens up about her journey through clinical research and why she chose to participate. Hosts Emily O’Brien and Manesh Patel, joined by Jenny Cook, talk about the life-saving potential of clinical trials and the real impact they have on patients and science. Hear Katie’s inspiring story and the rea…
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Bridging Science and Policy: A Conversation with Dr. Robert Califf
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31:07In this episode of Beyond the Endpoint, former FDA commissioner Dr. Robert Califf joins hosts Manesh Patel and Emily O’Brien to discuss critical challenges shaping the future of patient care. From misinformation to regulatory science to the financialization of healthcare, Dr. Califf has unique insight into the evolving healthcare landscape and the …
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Beyond the Headlines: What’s trending in medical news?
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25:52Ozempic curbing alcohol cravings, ADHD linked to shorter life expectancy, and an NBA rising star diagnosed with DVT—what does the science actually say? In this first episode of Beyond the Headlines, a new Beyond the Endpoint series, hosts Emily O’Brien and Manesh Patel break down the research behind these trending stories.Access resources related t…
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Wearables in Clinical Research: Data, Trends, and Challenges
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35:31Smartwatches, fitness trackers, and health data—how are wearables reshaping clinical research? In this episode, Dr. Marat Fudim joins us for an insightful discussion on how wearable technology is shaping the way we monitor health and conduct research. Topics include: • Are wearables improving patient care or just tracking steps? • How do researcher…
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The Intersection of Politics and Medicine: Impacts on Clinical Practice
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32:37In this episode of Beyond the Endpoint, Emily O’Brien and Manesh Patel sit down with Leslie Curtis, former senior FDA policy advisor, to explore the FDA’s role in balancing science, public health, and regulation, along with how political transitions influence clinical research, healthcare funding, and the approval process for new treatments.🔗 Acces…
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Bending the Curve on Hypertension
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34:18Reducing hypertension risk isn’t just about cutting salt. This week on Beyond The Endpoint, Emily O’Brien, Manesh Patel, and Jenny Cook talk with Dr. Dhruv Kazi about the complex public health battle against hypertension. From interventions to strategies for patient and physician adherence, this episode covers scalable solutions to change the futur…
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Caring Through Loss: The Role of Grief in Clinical Settings
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34:56In this episode of "Beyond the Endpoint," hosts Emily O'Brien and Manesh Patel are joined by guest host Jenny Cook to discuss grief among healthcare providers with Tony Galanos, a researcher and physician at the Duke University School of Medicine. Galanos — "Dr. G" as he's called around Duke — shares insights from his 12-year program helping other …
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Inviting Our Colleagues To Participate In DCRI On Record by Duke Clinical Research InstituteDuke Clinical Research Institute által
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John Shepherd And Michele Nolen by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Assessing Results of Open-label, Comparative Effectiveness Trials for Cardio-metabolic Drugs
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17:03Assessing Results of Open-label, Comparative Effectiveness Trials for Cardio-metabolic Drugs by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Duke IBD Podcast Series: IBD and Nutrition
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14:55Duke IBD Podcast Series: IBD and Nutrition by Duke Clinical Research InstituteDuke Clinical Research Institute által
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IBD Podcast with Dr. Jane Onken
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23:44IBD Podcast with Dr. Jane Onken by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Patient Perspective Nutrition And Diet In Perioperative Recovery
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14:59Patient Perspective Nutrition And Diet In Perioperative Recovery by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Nutrition In ERAS: " A Call For Clinical Trials"
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20:55Nutrition In ERAS: " A Call For Clinical Trials" by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Data, Innovation & Guidelines in Gastroenterology – Deborah Fisher, MD
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10:39Data, Innovation & Guidelines in Gastroenterology – Deborah Fisher, MD by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Sunil Rao at TCT 2018: Meeting Highlights and the #RadialFirst Journey by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Renato Lopes at TCT 2018: SECURE-PCI and Timing for Statin Dosing
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10:00Renato Lopes at TCT 2018: SECURE-PCI and Timing for Statin Dosing by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Jennifer Rymer at TCT 2018: Aborted TAVR Procedures and Same-Day Discharge for PCI
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10:22Jennifer Rymer at TCT 2018: Aborted TAVR Procedures and Same-Day Discharge for PCI by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Nutrition in Surgery – The Clinician’s Perspective
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27:01Nutrition in Surgery – The Clinician’s Perspective by Duke Clinical Research InstituteDuke Clinical Research Institute által
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The Role of the Dietician in Perioperative Nutrition Screening and Care
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20:46The Role of the Dietician in Perioperative Nutrition Screening and Care by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Perioperative Nutrition Optimization Clinics: The Future of Perioperative Care
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23:05Perioperative Nutrition Optimization Clinics: The Future of Perioperative Care by Duke Clinical Research InstituteDuke Clinical Research Institute által
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The Role of Nutrition in 'Strong for Surgery'
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27:03The Role of Nutrition in 'Strong for Surgery' by Duke Clinical Research InstituteDuke Clinical Research Institute által
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Science is the Best Medicine - EP7
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17:42What are clinical trials? Who should participate in them? And why are they important? In this episode of Science is the Best Medicine, Abhinav Sharma talks to Harvard’s Eugene Braunwald, MD, a cardiologist who’s been a firsthand witness to more than 50 years of clinical trials.Duke Clinical Research Institute által
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Science is the Best Medicine - EP6
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37:41Duke’s Mona Fiuzat, PhD, talks with Abhinav Sharma about how scientific discoveries are translated to usable treatments and how the U.S. Food and Drug Administration really works.Duke Clinical Research Institute által
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Science is the Best Medicine - EP5
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31:19Cardiologist Joseph Hill, MD, PhD, editor-in-chief of Circulation, discusses what it’s like to run a peer-reviewed journal and how medical discoveries are disseminated in the age of information overload.Duke Clinical Research Institute által
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Science is the Best Medicine - EP4
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23:09Medicare, Obamacare, rising costs, and preexisting conditions: The controversy over health care in the United States rages on in Congress and online. In this episode Mark McClellan, director of the Margolis Center for Health Policy and former U.S. Food and Drug Administration commissioner, discusses the complexities of healthcare policy.…
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Science is the Best Medicine - EP3
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26:57Robert Lefkowitz, MD, won the Nobel Prize for Chemistry in 2012 for his groundbreaking work on the proteins known as receptors. That research has since influenced the development of a wide variety of drugs including antihistamines, ulcer drugs, and beta blockers. In this episode of the podcast, he discusses his research, his family, and the path th…
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Science is the Best Medicine - EP2
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15:35Every year, more than two million people in the United States get infections that are resistant to antibiotics and at least 23,000 people die as a result, according to the Centers for Disease Control. These so-called "superbugs" represent one of the major public health threats facing the world today. In this episode, Ephraim Tsalik, MD, PhD, discus…
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Science is the Best Medicine - EP1
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36:38Chronic kidney disease (CKD) is among the most common diseases in the United States, affecting approximately 14 percent of the adult population. The disease, which often goes unnoticed until its advanced stages, can increase the risk of heart attack, stroke, or other serious medical conditions. In this episode of Science is the Best Medicine, Abhin…
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